Lampros Bisdounis

I am a DPhil student, working between the departments of clinical neuroscience and psychiatry. My work is supervised by Dr Simon Kyle, Dr Kate Saunders, and Prof Colin Espie, and is funded by the Medical Research Council Doctoral Training Partnership and the Nuffield Department of Clinical Neurosciences.

My doctoral research focuses on the interplay between sleep, circadian rhythms, and bipolar disorder. From its earliest conceptualisation as a psychiatric disorder in 1921 by Emil Kraepelin, bipolar disorder was diagnostically associated with a range of sleep problems. Now, 100 years later, the causal ordering between sleep, circadian, and mood disruptions has yet to be thoroughly examined. So, my DPhil research explores: (a) the profile of sleep and circadian disturbances in patients with bipolar disorder and high-risk individuals, (b) the putative mechanism linking sleep disruption to mood symptomatology, and (c) the therapeutic capacity of sleep and circadian interventions in bipolar disorder. 

In addition to my primary research focus, I am a Fellow of Reproducible Research Oxford and a big advocate for open science. Finally, I work alongside Prof Anne Duffy in the U-Flourish project, looking at mental wellbeing predictors of academic achievement.