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Publications

Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.

Dai X-Q. et al, (2022), Cell Metab, 34, 256 - 268.e5

Gap junction coupling and islet delta-cell function in health and disease

Miranda C. et al, (2022), Peptides, 147

Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes.

Kim A. et al, (2021), Elife, 10

Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes

Kim A. et al, (2021), eLife

The importance of islet delta-cell ATP-sensitive K(+)channel (K-ATP) function for somatostatin secretion and islet hormone balance

Hill TG. et al, (2021), DIABETOLOGIA, 64, 64 - 64

Communication between pancreatic endocrine cells is modulated by neural signalling

Yang YHC. et al, (2021), DIABETIC MEDICINE, 38

Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high fat diet

KELLARD J. et al, (2020), Molecular Metabolism

Vitamin D-binding protein contributes to the maintenance of α-cell function 2 and glucagon secretion

VILORIA K. et al, (2020), Cell Reports

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

Carrat GR. et al, (2020), Molecular Metabolism, 101015 - 101015

Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells

Vergari E. et al, (2019), Nature Metabolism

Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo

Salem V. et al, (2019), Nature Metabolism

Increased Pancreatic a Cell Ca(2+)Oscillations Explain Hyperglucagonemia in High-Fat Diet-Fed Mice

Kellard J. et al, (2019), DIABETES, 68

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.

Vergari E. et al, (2019), Nat Commun, 10

Glucose regulates pancreatic islet beta cell calcium dynamics and intercellular connectivity in vivo

Salem V. et al, (2018), DIABETOLOGIA, 61, S18 - S18

Pancreatic alpha cells respond to glucose with a change in the frequency of intracellular calcium oscillations

Kellard JA. et al, (2018), DIABETOLOGIA, 61, S244 - S244

GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca2+ channels

BRIANT L. et al, (2018), Physiological Reports

Beta-cell hubs maintain Ca2+ oscillations in human and mouse islet simulations

Briant L. et al, (2018), Islets

Pancreatic Alpha-Cell Function and Identity in Human T2D

Dai X. et al, (2018), DIABETES, 67

CPT1a-dependent long-chain fatty acid oxidation contributes to maintaining glucagon secretion from pancreatic islets

Briant LJB. et al, (2018), Cell Reports

δ- and β-cells are electrically coupled and regulate α-cell activity via somatostatin

Briant LJBB. et al, (2017), The Journal of Physiology

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