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Growing evidence suggests that the recognition of different emotional states involves at least partly separable neural circuits. Here we assessed the discrimination of both anger and happiness in healthy subjects receiving transcranial magnetic stimulation (TMS) over the medial-frontal cortex or over a control site (mid-line parietal cortex). We found that TMS over the medial-frontal cortex impairs the processing of angry, but not happy, facial expressions of emotion.

Original publication




Journal article


Nat Neurosci

Publication Date





17 - 18


Adult, Analysis of Variance, Anger, Discrimination (Psychology), Electric Stimulation, Facial Expression, Female, Frontal Lobe, Humans, Magnetic Resonance Imaging, Male, Parietal Lobe, Pattern Recognition, Visual, Photic Stimulation, Reaction Time, Transcranial Magnetic Stimulation