Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

To replicate the association between insomnia with objective short sleep duration and hypertension, type 2 diabetes and duration of insomnia.Retrospective case-control study.Department of Psychiatry and Psychotherapy, Medical Center-University of Freiburg.328 patients with primary insomnia classified according to DSM-IV criteria (125 males, 203 females, 44.3 ± 12.2 years).N/A.All participants were investigated using polysomnography, blood pressure measurements, and fasting routine laboratory.Insomnia patients with short sleep duration (< 6 hours) in the first night of laboratory sleep presented with a longer duration of insomnia compared to those with normal sleep duration (≥ 6 hours) in the first night of laboratory sleep. Insomnia patients who were categorised as short sleepers in either night were not more likely to suffer from hypertension (systolic blood pressure of ≥ 140 mm Hg, diastolic blood pressure of ≥ 90 mm Hg, or a previously established diagnosis). Data analysis showed that insomnia patients with objective short sleep duration were not more likely to suffer from type 2 diabetes (fasting plasma glucose level of ≥ 126 mg/dl, or a previously established diagnosis). However, the diabetes analysis was only based on a very small number of diabetes cases. As a new finding, insomnia patients who were categorised as short sleepers in either night presented with increases in liver enzyme levels.The finding on insomnia duration supports the concept of two distinct sub-groups of insomnia, namely insomnia with, and without, objectively determined short sleep duration. However, our data challenges previous findings that insomnia patients with short sleep duration are more likely to suffer from hypertension.

Original publication

DOI

10.1371/journal.pone.0180339

Type

Journal article

Journal

PloS one

Publication Date

26/07/2017

Volume

12

Pages

e0180339 - e0180339

Addresses

Medical Psychology and Medical Sociology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Keywords

Humans, Sleep Initiation and Maintenance Disorders, Hypertension, Diabetes Mellitus, Type 2, Blood Glucose, Polysomnography, Risk Factors, Regression Analysis, Case-Control Studies, Retrospective Studies, Sleep, Blood Pressure, Time Factors, Diagnostic and Statistical Manual of Mental Disorders, Adult, Middle Aged, Female, Male