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Circadian Therapeutics has been established to identify and bring to market pharmaceutical and diagnostic platforms for the effective management of physiological and pathological conditions through their ability to modify the body's circadian rhythms.
Guideline clarification: dropout in FDA-cleared dCBT-I is comparable to pharmacotherapy and therapist-delivered CBT-I
Journal article
Henry AL. et al, (2026), Journal of Clinical Sleep Medicine, 22
The role of therapeutic alliance in psilocybin treatment for treatment-resistant depression: A post hoc path analysis.
Journal article
Goodwin GM. et al, (2026), J Affect Disord, 406
Development and validation of the Tiredness Identification Index (TIDI): a combined scale for the assessment of fatigue and sleepiness
Journal article
Reeve S. et al, (2026), SLEEP Advances
Physiologically relevant media are associated with overlapping metabolic responses in primary human hepatocytes and Huh7 cells.
Journal article
Cross E. et al, (2026), Physiol Rep, 14
Evaluating Open-Source Wrist-Worn Accelerometer Models for Sedentary Time Detection Against Thigh-Worn Accelerometer Data
Preprint
Acquah A. et al, (2026)
Metabolic state determines the brain and direct islet effects of liraglutide on enhanced insulin secretion.
Journal article
Saponaro C. et al, (2026), Diabetologia
Pharmacokinetics and pharmacodynamics of orally administered S-ketamine in healthy participants.
Journal article
van Mechelen JC. et al, (2026), J Psychopharmacol
A highly efficient method to differentiate CGRP-expressing peptidergic nociceptors from human induced pluripotent stem cells.
Journal article
Duggal G. et al, (2026), Stem Cell Reports
Sustained pharmacodynamic effects of S-ketamine on cortical excitability and resting-state brain activity: A randomized, placebo-controlled trial.
Journal article
de Cuba CMKE. et al, (2026), Br J Clin Pharmacol
Genotypic and Phenotypic Insights on 11 Novel Variants in the ABCA4 Gene
Journal article
Al-Khuzaei S. et al, (2026), Genes, 17, 728 - 728
A hippocampal neuroimaging signature of neurovascular insulin signalling links metabolism to mood
Preprint
Cherix A. et al, (2026)
Digital twin reconstruction of ventricular repolarisation identifies regional causes of T-wave abnormalities in hypertrophic cardiomyopathy
Preprint
Coleman JA. et al, (2026)
High Basal Skeletal Muscle Glucose Uptake in Normoglycemic and Hyperinsulinemic Overweight Men is Coupled With an Increase in the Alanine-Glucose Cycling.
Journal article
Blicher LH. et al, (2026), Diabetes
Joint association of genetic risk and accelerometer-based step count with cardiovascular disease: a UK-Biobank cohort study.
Journal article
Birmpili P. et al, (2026), Eur J Prev Cardiol
Automated virtual reality therapy to treat needle fears (trypanophobia) in adolescents in England: a proof-of-concept cohort study and a Phase II randomised controlled trial
Journal article
FREEMAN D., (2026), EClinicalMedicine
Effects on hippocampal activity following novel 5-HT4 receptor agonism in unmedicated patients with depression: the RESTAND study
Journal article
MURPHY S., (2026), Translational Psychiatry
Pro-cognitive effects of 5-HT4 receptor agonism in individuals with remitted depression
Journal article
MURPHY S., (2026), Psychological Medicine
Step count recovery patterns in the first six weeks after knee replacement in individuals with knee osteoarthritis: a secondary analysis of a prospective observational cohort study using wrist-worn accelerometry.
Journal article
Olanrewaju AE. et al, (2026), Rheumatol Int, 46
Sleep immediately after noise overexposure worsens tinnitus in mice
Preprint
Milinski L. et al, (2026)
The Motor Neuron Disease Register for England, Wales, and Northern Ireland: Protocol for a Population Register.
Journal article
Biondi A. et al, (2026), JMIR Res Protoc, 15